AFC Bournemouth are unbeaten in six home matches against Huddersfield Town in all competitions (W3 D3), since losing 1-0 in League One in August 2007.
Huddersfield have not won a midweek top-flight match (Tuesday, Wednesday or Thursday) since March 1971. They have drawn six and lost eight fixtures since then.
After their 2-0 win at Wolverhampton Wanderers in their last away match, Huddersfield are looking to secure back-to-back top-flight victories on the road for the first time since April 1956.
Each of Brighton’s last seven Premier League victories have been by a one-goal margin. They last won by more in February, beating Swansea City 4-1.
Brighton have not won any of their six midweek PL matches, on a Tuesday, Wednesday or Thursday. They have drawn three and lost three of those.
West Ham have won their last six matches in all competitions against Cardiff, scoring 14 goals and conceding just two.
However, the Hammers have lost their last three home Premier League matches against promoted sides, more than in their previous 17 such clashes in the competition. They have never lost four consecutive top-flight home matches against promoted sides.
No PL team has won more matches after coming from behind this season than Cardiff, with all three of their victories coming in such a manner.
Watford are winless in their eight PL meetings with Man City and have lost the last six in a row.
However, the Hornets have beaten the reigning champions at home in each of the last two PL campaigns, beating Leicester City 2-1 in 2016/17 and Chelsea 4-1 last term.
Man City have won their last two away league matches against Watford 5-0 and 6-0. The only team to score five or more goals in three consecutive top-flight away fixtures against the same opponent is West Bromwich Albion, against Birmingham City between December 1957 and April 1960.
All seven of Liverpool’s PL goals at Turf Moor have come in the second half.
The Reds are unbeaten in their last 16 PL matches played on a Wednesday (W11 D5), ever since a 3-1 loss at Stoke City on Boxing Day in 2012.
Liverpool have won just one of their last seven PL away matches against sides starting the day inside the relegation zone (D2 L4), although that victory came in their last such match at Huddersfield Town in October.
Everton have beaten Newcastle in eight of their last nine Premier League meetings and have won the last five clashes without conceding a single goal.
There have been more goals scored from penalties in PL meetings between Everton and Newcastle than in any other fixture in the competition, with 18.
Newcastle haven not won a midweek PL match since December 2013, when they beat Stoke City 5-1. They have since drawn eight and lost nine of their matches played on a Tuesday, Wednesday or Thursday.
This will be the first Premier League meeting between Fulham and Leicester since 2003/04, when the Cottagers won both meetings 2-0.
Leicester, who are unbeaten in five PL matches, last went longer without defeat in the competition in May 2016, when they had a 12-match undefeated run during their title-winning campaign under now-Fulham manager Claudio Ranieri.
Man Utd are unbeaten in their last 11 PL home matches against Arsenal, since a 1-0 loss in September 2006.
United, who won both of their PL meetings with Arsenal last season, can now secure a third consecutive victory over them for the first time since November 2012.
This is the first time United have hosted Arsenal in a midweek PL match since 8 May 2002, when the Gunners won 1-0 to clinch the title thanks to a Sylvain Wiltord strike.
Arsenal have lost their last three midweek PL matches played on a Tuesday, Wednesday or Thursday and conceded three goals in each defeat against Swansea City, Manchester City and Leicester City last season.
Spurs have won eight of their last 10 PL home matches against Southampton, losing only in September 2003 and May 2016.